L-Karnitin

L-karnitin er en hastighetsbegrensende faktor for fettsyreoksidasjon. Det hjelper å brenne lipider i cellene for å produsere ekstra energi

Ingrediensene i Enedria™ virker i kombinasjon og gir en synergistisk effekt:

Kosttilskuddet Enedria™ retter seg primært mot kardiometabolsk syndrom, og ble utviklet ved å kombinere ulike ingredienser som hver for seg har dokumentert potensial til å øke mitokondriefunksjonen.

Formuleringen er en kombinasjon av marine oljer fra fisk og alger, peptider fra fisk, samt hjelpestoffene astaxanthin og L-karnitin. Effektene og kombinasjonen av ingrediensene er additiv og synergistisk, og tallrike dyrestudier har fastslått at lipid ekstrakter og bioaktive peptider, alene og i kombinasjon, er svært lovende ingredienser i forhold til aldring og livsstilsrelaterte sykdommer.

De synergistiske effektene mellom oljer og peptider er patentert, og kliniske studier på mennesker av de individuelle komponentene i Enedria™ er gjennomført.

Internasjonale vitenskapelige tidsskrifter:

  1. Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation.
  2. Eicosapentaenoic and docosahexaenoic acid affect mitochondrial and peroxisomal fatty acid oxidation in relation to substrate preference.
  3. Effects of long-chain monounsaturated and n-3 fatty acids on fatty acid oxidation and lipid composition in rats.
  4. Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats.
  5. Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats.
  6. The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis.
  7. The hypotriglyceridemic effect of dietary n-3 FA is associated with increased beta-oxidation and reduced leptin expression.
  8. In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.
  9. Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study.
  10. Effect of a high-fat diet with partially hydrogenated fish oil on long-chain fatty acid metabolizing enzymes in subcellular fractions of rat liver.
  11. On the effect of peroxisomal beta-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats.
  12. Eicosapentaenoic acid causes transient accumulation of lipids in rat myocardium.
  13. Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed the fatty acid composition in rat blood and organs.
  14. Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia.
  15. EPA and DHA possess different metabolic properties.
  16. Fatty acid composition in chronic heart failure: low circulating levels of eicosatetraenoic acid and high levels of vaccenic acid are associated with disease severity and mortality.
  17. Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study.
  18. Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure.
  19. Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection.
  20. Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults – a pilot study.
  21. The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
  22. Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals.
  23. Hepatic Energy Metabolism Underlying Differential Lipidomic Responses to High-Carbohydrate and High-Fat Diets in Male Wistar Rats.
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