L-Karnitin
L-karnitin er en hastighetsbegrensende faktor for fettsyreoksidasjon. Det hjelper å brenne lipider i cellene for å produsere ekstra energi
Ingrediensene i Enedria™ virker i kombinasjon og gir en synergistisk effekt:
Kosttilskuddet Enedria™ retter seg primært mot kardiometabolsk syndrom, og ble utviklet ved å kombinere ulike ingredienser som hver for seg har dokumentert potensial til å øke mitokondriefunksjonen.
Formuleringen er en kombinasjon av marine oljer fra fisk og alger, peptider fra fisk, samt hjelpestoffene astaxanthin og L-karnitin. Effektene og kombinasjonen av ingrediensene er additiv og synergistisk, og tallrike dyrestudier har fastslått at lipid ekstrakter og bioaktive peptider, alene og i kombinasjon, er svært lovende ingredienser i forhold til aldring og livsstilsrelaterte sykdommer.
De synergistiske effektene mellom oljer og peptider er patentert, og kliniske studier på mennesker av de individuelle komponentene i Enedria™ er gjennomført.
Internasjonale vitenskapelige tidsskrifter:
- Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation.
- Eicosapentaenoic and docosahexaenoic acid affect mitochondrial and peroxisomal fatty acid oxidation in relation to substrate preference.
- Effects of long-chain monounsaturated and n-3 fatty acids on fatty acid oxidation and lipid composition in rats.
- Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats.
- Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats.
- The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis.
- The hypotriglyceridemic effect of dietary n-3 FA is associated with increased beta-oxidation and reduced leptin expression.
- In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.
- Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study.
- Effect of a high-fat diet with partially hydrogenated fish oil on long-chain fatty acid metabolizing enzymes in subcellular fractions of rat liver.
- On the effect of peroxisomal beta-oxidation and carnitine palmitoyltransferase activity by eicosapentaenoic acid in liver and heart from rats.
- Eicosapentaenoic acid causes transient accumulation of lipids in rat myocardium.
- Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed the fatty acid composition in rat blood and organs.
- Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia.
- EPA and DHA possess different metabolic properties.
- Fatty acid composition in chronic heart failure: low circulating levels of eicosatetraenoic acid and high levels of vaccenic acid are associated with disease severity and mortality.
- Dietary intake of n-3 long-chain polyunsaturated fatty acids and risk of myocardial infarction in coronary artery disease patients with or without diabetes mellitus: a prospective cohort study.
- Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure.
- Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection.
- Krill oil reduces plasma triacylglycerol level and improves related lipoprotein particle concentration, fatty acid composition and redox status in healthy young adults – a pilot study.
- The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
- Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals.
- Hepatic Energy Metabolism Underlying Differential Lipidomic Responses to High-Carbohydrate and High-Fat Diets in Male Wistar Rats.